1. Fr. John Otto Bredeick – 1844-1858
2. Fr. Francis Westerholt – 1858-1868
3. Fr. Aloysius Hoeffel – 1868-1909
4. Fr. Frederick Rupert – 1910-1936; later appointed as Monsignor Rupert
5. Fr. John L. Sassen, Ph.D. – 1936-1940
6. Fr. Carl F. Reineck – 1940-1962; later appointed as Monsignor Reineck
7. Fr. Joseph Ignatius Schill – 1962-1968
8. Fr. Albert Ottenweller – 1968-1976; later appointed as Bishop Ottenweller
9. Fr. Arthur Badger – 1976-1981
10. Fr. Robert Sidner – 1981-1985
11. Fr. James Peiffer – 1986-1996
12. Fr. Thomas Gorman – 1996-2006
13. Fr. Melvin Verhoff – 2006-2013
14. Fr. David Reinhart – 2013-2014
15. Fr. Dennis Walsh – 2015-present
*Fr. George Lang: Served as interim pastor/administrator from September 1909-January 1910 (until new pastor appointed)
*Fr. Ronald Schock: Served as interim pastor/parochial administrator from November 2014-February 2015